Journal article
Prognostic Impact of Heart Failure History in Patients with Secondary Mitral Regurgitation Treated by MitraClip.
- Adamo M Cardiothoracic Department, Civil Hospitals and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University, Brescia, Italy. Electronic address: mariannaadamo@hotmail.com.
- Gavazzoni M Heart Center, Zürich University Hospital, University of Zürich, Zürich, Switzerland.
- Castiello A Cardiothoracic Department, Civil Hospitals and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University, Brescia, Italy.
- Estevez-Loureiro R Interventional Cardiology Unit, Hospital Álvaro Cunqueiro, Vigo, Spain.
- Taramasso M Heart Center, Zürich University Hospital, University of Zürich, Zürich, Switzerland.
- Lupi L Cardiothoracic Department, Civil Hospitals and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University, Brescia, Italy.
- Branca L Cardiothoracic Department, Civil Hospitals and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University, Brescia, Italy.
- Portoles A University Hospital Puerta de Hierro-Majadahonda, Madrid, Spain.
- Benito-Gonzalez T University Hospital of Leon, Leon, Spain.
- Curello S Cardiothoracic Department, Civil Hospitals and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University, Brescia, Italy.
- Maisano F Heart Center, Zürich University Hospital, University of Zürich, Zürich, Switzerland.
- Metra M Cardiothoracic Department, Civil Hospitals and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University, Brescia, Italy.
- 2020-08-31
Published in:
- The American journal of cardiology. - 2020
English
The aim of this study was to investigate the prognostic role of heart failure (HF) history in patients with secondary mitral regurgitation (SMR) underwent MitraClip. We retrospectively analyzed 186 patients with SMR undergoing MitraClip at 4 centres. HF history was defined as number or days of HF hospitalizations in the 12-month before MitraClip, or as time from last HF hospitalization to MitraClip, or time between first SMR diagnosis and MitraClip. More severe symptoms were observed in patients with >1 HF hospitalization compared with those with ≤1 HF hospitalizations, in those with ≥10 days versus <10 days of HF hospitalization and in those with shortest time from the last HF hospitalization. No significant differences were observed for procedural data in the population stratified according to the different definitions. In variables related with HF history, only the number of HF hospitalizations before MitraClip was associated with an increased risk of clinical events (hazard ratio 1.59; 95% confidence interval [1.09 to 2.12]; p = 0.015), whereas days of previous HF hospitalization, time from last HF hospitalization and from first diagnosis of SMR do not impact on prognosis. A significant decrease in the number and days of HF hospitalizations was observed in the 12-month after MitraClip compared with the 12-month before. In conclusion, in variables related with HF history, recurrence (>1) of HF hospitalizations before MitraClip was the most powerful predictor of prognosis. Latency of intervention did not affect outcomes.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.amjcard.2020.08.037
- PMID 32861737
- Persistent URL
- https://sonar.rero.ch/global/documents/82598
Statistics
Document views: 13
File downloads: