Neutralization of insulin by photocleavage under high vacuum.
Journal article

Neutralization of insulin by photocleavage under high vacuum.

  • Schätti J Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch.
  • Kriegleder M Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Debiossac M Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Kerschbaum M Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Geyer P Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Mayor M Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch and Institute of Nanotechnology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany and Lehn Institute of Functional Materials (LIFM), Sun Yat-Sen University (SYSU), XinGangXi Road 135, 510275 Guangzhou, P. R. China.
  • Arndt M Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Köhler V Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch.
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  • 2019-10-03
Published in:
  • Chemical communications (Cambridge, England). - 2019
English Charge reduction and neutralization of electro-sprayed peptides are realized by selective gas-phase photocleavage of tailored covalent tags. The concept is demonstrated with four model peptides in positive and negative ion modes and tagged insulin as the largest construct.
Language
  • English
Open access status
hybrid
Identifiers
Persistent URL
https://sonar.rero.ch/global/documents/247007
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