Journal article
Solvent effect on palladium-catalyzed cross-coupling reactions and implications on the active catalytic species.
- Proutiere F Laboratorium für Organische Chemie, ETH Zürich, Switzerland.
- Schoenebeck F
- 2011-07-14
Published in:
- Angewandte Chemie (International ed. in English). - 2011
English
Suzuki coupling of the bifunctional substrate 1 using [Pd(2)(dba)(3)]/PtBu(3) gives selectivity for C-Cl in nonpolar solvents but for C-OTf in polar solvents. The results of computational and experimental studies suggest that the catalytically active species in polar solvents under conditions employing coordinating additives is inconsistent with monoligated [Pd(PtBu(3))]. Instead, the data are consistent with an anionic palladium complex as the active species.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1002/anie.201101746
- PMID 21751309
- Persistent URL
- https://sonar.rero.ch/global/documents/223069
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