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Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO).

  • Soffietti R Department of Neuro-Oncology, University and City of Health and Science Hospital, Turin, Italy.
  • Abacioglu U Department of Radiation Oncology, Neolife Medical Center, Istanbul, Turkey.
  • Baumert B Department of Radiation-Oncology, MediClin Robert-Janker-Klinik, Bonn, Germany.
  • Combs SE Department of Innovative Radiation Oncology and Radiation Sciences, Munich, Germany.
  • Kinhult S Department of Oncology, Skane University Hospital, Lund, Sweden.
  • Kros JM Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Marosi C Department of Internal Medicine, Division of Oncology, Medical University, Vienna, Austria.
  • Metellus P Department of Internal Medicine, Division of Oncology, Medical University, Vienna, Austria.
  • Radbruch A Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Villa Freixa SS Department of Radiation Oncology, Institut Català d'Oncologia, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
  • Brada M Department of Molecular and Clinical Cancer Medicine & Radiation Oncology, Liverpool, United Kingdom.
  • Carapella CM Department of Neuroscience, Division of Neurosurgery, Regina Elena Nat Cancer Institute, Rome, Italy.
  • Preusser M Department of Medicine I and Comprehensive Cancer Center CNS Unit (CCC-CNS), Medical University of Vienna, Vienna, Austria.
  • Le Rhun E Department of Neurosurgery, Neuro-oncology, University Hospital, Lille, France.
  • Rudà R Department of Neuro-Oncology, University and City of Health and Science Hospital, Turin, Italy.
  • Tonn JC Department of Neurosurgery, University of Munich LMU, Munich, Germany.
  • Weber DC Centre for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
  • Weller M Department of Neurology, University Hospital Zurich, Zurich, Switzerland.
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  • 2017-04-10
Published in:
  • Neuro-oncology. - 2017
brain metastases
chemotherapy
neuroimaging
neuropathology
stereotactic radiosurgery/stereotactic fractionated radiotherapy
supportive care
surgery
targeted therapy
whole-brain radiation therapy
Brain Neoplasms
Humans
Neoplasms
Practice Guidelines as Topic
English The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.
Language
  • English
Open access status
green
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Persistent URL
https://sonar.rero.ch/global/documents/191272
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