Journal article
The silver anniversary of gold: 25 years of the colloidal gold marker system for immunocytochemistry and histochemistry.
- Roth J Department of Pathology, University of Zürich, Switzerland.
- 1996-07-01
Published in:
- Histochemistry and cell biology. - 1996
English
Since 1971, when W.P. Faulk and G.M. Taylor published "An immunocolloid method for the electron microscope", colloidal gold has become a very widely used marker in microscopy. It has been used to detect a huge range of cellular and extracellular constituents by in situ hybridization, immunogold, lectin-gold, and enzyme-gold labeling. Besides its use in light microscopic immunogold and lectin-gold silver staining, colloidal gold remains the label of choice for transmission electron microscopy studying thin sections, freeze-etch, and surface replicas, as well as for scanning electron microscopy. The year 1996 is the 25th anniversary of the introduction of colloidal gold as a marker in immunoelectron microscopy and this overview outlines some of the major milestones in the development of the colloidal gold marker system.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1007/bf02473197
- PMID 8858362
- Persistent URL
- https://sonar.rero.ch/global/documents/188462
Statistics
Document views: 17
File downloads: