Back
Repetitive discharge due to self-ephaptic excitation of a motor unit.
Journal article

Repetitive discharge due to self-ephaptic excitation of a motor unit.

  • Roth G Division of Clinical Neurophysiology, University Hospital, Geneva, Switzerland.
  • 1994-02-01
Published in:
  • Electroencephalography and clinical neurophysiology. - 1994
Action Potentials
Aged
Carpal Tunnel Syndrome
Charcot-Marie-Tooth Disease
Electric Stimulation
Female
Humans
Male
Motor Neurons
Muscle Denervation
Peripheral Nerves
English Repetitive discharges (RDs) of a motor unit action potential were evoked by nerve stimulation in chronically denervated muscles of 3 patients. One RD also occurred at rest and during voluntary contraction. The 3 RDs had a regular firing frequency of respectively 16, 27 and 28.5 c/sec. Double stimulation evoked an RD consisting of doublets. An ectopic discharge arising during the RD had the same effect. These observations make likely that such RDs result from a 1-way ephaptic reverberating excitation occurring within a single MU. The synchronized potential of muscle fibres grouped by reinnervation may re-excite an axonal branch of the same MU, thus initiating a reverberating loop.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.rero.ch/global/documents/174912
Statistics
Document views: 7 File downloads: