![2,6-Diazaspiro[3.3]heptanes: synthesis and application in Pd-catalyzed aryl amination reactions.](/static/images/no-image.png)
Journal article
2,6-Diazaspiro[3.3]heptanes: synthesis and application in Pd-catalyzed aryl amination reactions.
- Burkhard J Laboratorium für Organische Chemie, ETH Zürich, CH-8093 Zürich, Switzerland.
- Carreira EM
- 2008-07-18
Published in:
- Organic letters. - 2008
Amination
Azetidines
Catalysis
Cyclization
Molecular Structure
Palladium
Piperazine
Piperazines
Spiro Compounds
Stereoisomerism
English
A concise and scalable synthesis of a 2,6-diazaspiro[3.3]heptane building block is reported. The usefulness of this structural surrogate of piperazine is shown in arene amination reactions yielding a variety of N-Boc- N'-aryl-2,6-diazaspiro[3.3]heptanes.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1021/ol801293f
- PMID 18630921
- Persistent URL
- https://sonar.rero.ch/global/documents/164197
Statistics
Document views: 52
File downloads: