The effect of saliva substitutes on enamel erosion in vitro.
- Aykut-Yetkiner A University of Zurich, Clinic for Preventive Dentistry, Periodontology and Cariology, Zurich, Switzerland; University of Ege, Faculty of Dentistry, Department of Pediatric Dentistry, Izmir, Turkey. Electronic address: a_aykut@hotmail.com.
- Wiegand A Department of Preventive Dentistry, Periodontology and Cariology, University of Göttingen, Germany.
- Attin T University of Zurich, Clinic for Preventive Dentistry, Periodontology and Cariology, Zurich, Switzerland.
- 2014-04-08
Published in:
- Journal of dentistry. - 2014
Dry mouth
Enamel erosion
Saliva substitutes
Aerosols
Animals
Cattle
Cellulose
Citric Acid
Dental Enamel
Diamines
Drug Combinations
Fluorides
Gels
Glucose Oxidase
Hydrogen-Ion Concentration
Lactoperoxidase
Materials Testing
Mouthwashes
Muramidase
Protective Agents
Saliva, Artificial
Sodium Fluoride
Tin Compounds
Tooth Demineralization
Tooth Erosion
Tooth Remineralization
Viscosity
English
OBJECTIVES
To investigate the effect of saliva substitutes on enamel erosion in vitro.
METHODS
A total of 204 bovine enamel samples were embedded in acrylic resin and allocated to 17 groups (n=12). The specimens were eroded in an artificial mouth (3 days; 6×30 s/days, flow rate: 2 ml/min) using citric acid (pH: 2.5). Immediately after the erosive attacks, saliva substitutes (12 sprays, 3 gels) were applied. Between the erosive cycles the specimens were rinsed with artificial saliva (flowrate: 0.5 ml/min). A SnCl2/AmF/NaF-containing mouthrinse was used as positive control, water spray served as negative control. Enamel loss was measured profilometrically and the data were analyzed using one-way ANOVA followed by Scheffé's post hoc tests (p<0.05).
RESULTS
Four saliva substitutes increased enamel erosion, probably due to the low pH or the content of citric acid. Several saliva substitutes were able to reduce enamel erosion significantly by 60-90% (in the range of the positive control). The protective potential of these products was in the range of the positive control (reduction of enamel loss to 30% of negative control). The erosion-protective potential of these high-viscous products is probably related to their film-forming properties, leading to a mechanical protection of the surface.
CONCLUSION
Saliva substitutes containing a very low pH exhibit a distinct erosive potential, while most high-viscous products present an erosion-protective effect. It can be recommended that patients suffering from xerostomia and at high risk for dental erosion should use high-viscous saliva substitutes, but should avoid saliva substitutes with low pH or containing citric acid.
CLINICAL SIGNIFICANCE
It can be recommended that patients suffering from xerostomia and at high risk for dental erosion should use high-viscous saliva substitutes, but should avoid saliva substitutes with low pH or containing citric acid.
To investigate the effect of saliva substitutes on enamel erosion in vitro.
METHODS
A total of 204 bovine enamel samples were embedded in acrylic resin and allocated to 17 groups (n=12). The specimens were eroded in an artificial mouth (3 days; 6×30 s/days, flow rate: 2 ml/min) using citric acid (pH: 2.5). Immediately after the erosive attacks, saliva substitutes (12 sprays, 3 gels) were applied. Between the erosive cycles the specimens were rinsed with artificial saliva (flowrate: 0.5 ml/min). A SnCl2/AmF/NaF-containing mouthrinse was used as positive control, water spray served as negative control. Enamel loss was measured profilometrically and the data were analyzed using one-way ANOVA followed by Scheffé's post hoc tests (p<0.05).
RESULTS
Four saliva substitutes increased enamel erosion, probably due to the low pH or the content of citric acid. Several saliva substitutes were able to reduce enamel erosion significantly by 60-90% (in the range of the positive control). The protective potential of these products was in the range of the positive control (reduction of enamel loss to 30% of negative control). The erosion-protective potential of these high-viscous products is probably related to their film-forming properties, leading to a mechanical protection of the surface.
CONCLUSION
Saliva substitutes containing a very low pH exhibit a distinct erosive potential, while most high-viscous products present an erosion-protective effect. It can be recommended that patients suffering from xerostomia and at high risk for dental erosion should use high-viscous saliva substitutes, but should avoid saliva substitutes with low pH or containing citric acid.
CLINICAL SIGNIFICANCE
It can be recommended that patients suffering from xerostomia and at high risk for dental erosion should use high-viscous saliva substitutes, but should avoid saliva substitutes with low pH or containing citric acid.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1016/j.jdent.2014.03.012
- PMID 24705070
- Persistent URL
- https://sonar.rero.ch/global/documents/161044
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