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The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis.

  • Metsios GS Faculty of Education, Health and Wellbeing, University of Wolverhampton, Gorway Road, Walsall Campus, Walsall, WS13BD, UK. g.metsios@wlv.ac.uk.
  • Moe RH Department of Rheumatology, National Resource Centre for Rehabilitation in Rheumatology, Diakonhjemmet Hospital, Oslo, Norway.
  • van der Esch M ACHIEVE-Center of Applied Research, Faculty of Health, Reade, Center for Rehabilitation and Rheumatology/Amsterdam Rehabilitation Research Center, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
  • van Zanten JJCSV School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
  • Fenton SAM School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
  • Koutedakis Y School of Physical Education and Sport Science, University of Thessaly, Volos, Greece.
  • Vitalis P Faculty of Education, Health and Wellbeing, University of Wolverhampton, Gorway Road, Walsall Campus, Walsall, WS13BD, UK.
  • Kennedy N School of Allied Health, Faculty of Education and Health Sciences and Health Research Institute, University of Limerick, Limerick, Ireland.
  • Brodin N Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge, Sweden.
  • Bostrom C Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge, Sweden.
  • Swinnen TW Division of Rheumatology, University Hospitals Leuven, Leuven, Belgium.
  • Tzika K Faculty of Education, Health and Wellbeing, University of Wolverhampton, Gorway Road, Walsall Campus, Walsall, WS13BD, UK.
  • Niedermann K School of Health Professions, Institute of Physiotherapy, Zurich University of Applied Sciences, Winterthur, Switzerland.
  • Nikiphorou E Department of Academic Rheumatology, King's College London, London, UK.
  • Fragoulis GE Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
  • Vlieland TPVM Department of Orthopaedics, Rehabilitation and Physical Therapy, Leiden University Medical Center, Leiden, The Netherlands.
  • Van den Ende CHM Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands.
  • Kitas GD Department of Rheumatology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
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  • 2019-12-06
Published in:
  • Rheumatology international. - 2020
Autoimmune disease
Cardiovascular disease
Exercise
Inflammation
Non-communicable disease
Physical activity
Rehabilitation
Rheumatoid arthritis
English Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) can significantly improve patient-reported and clinical index-assessed outcomes in RA. In addition to this, engagement in exercise programmes improves, in a dose-dependent manner, the risk of developing CVD as well as CVD symptoms and outcomes. The present narrative review uses evidence from systematic reviews and meta-analyses as well as controlled trials, to synthesize the current state-of-the-art on the potential effects of aerobic and resistance exercise on CVD risk factors as well as on cardiac and vascular function and structure in people with RA. Where there is a lack of evidence in RA to explain potential mechanisms, relevant studies from the general population are also discussed and linked to RA.
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  • English
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green
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https://sonar.rero.ch/global/documents/154543
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