A microcystic adnexal carcinoma in the auditory canal 15 years after radiotherapy of a 12-year-old boy with nasopharynx carcinoma.
- Beer KT Department of Radiation Oncology, Inselspital, University of Bern, Bern, Switzerland. karl.beer@radioonkologie.ch
- Bühler SS
- Mullis P
- Laeng RH
- Greiner R
- 2005-06-01
Published in:
- Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. - 2005
Carcinoma
Child
Cobalt Radioisotopes
Ear Neoplasms
Humans
Male
Nasopharyngeal Neoplasms
Neoplasms, Radiation-Induced
Radiotherapy
Time Factors
Treatment Outcome
English
BACKGROUND
Radiogenic malignancies require cure of the primary disease and a prolonged survival. The introduction of high-volt technology in the 1950s and 1960s made radical radiotherapy feasible and successful in terms of higher cure rates and longer survival. We are already in a time when a higher number of patients with radiogenic secondary malignancies must be expected.
CASE REPORT
A 12-year-old boy is reported who suffered from an advanced nasopharynx carcinoma and was treated with radical irradiation in 1983. 15 years later he developed a rare microcystic adnexal carcinoma of the auditory canal inside the volume of the target dose. The secondary malignant neoplasm was resected and required another radiation treatment (1 Gy b.i.d.) due to involved margins.
DISCUSSION AND LITERATURE REVIEW
The entity of microcystic carcinoma is discussed with a review of the literature on biology, diagnosis, and treatment.
Radiogenic malignancies require cure of the primary disease and a prolonged survival. The introduction of high-volt technology in the 1950s and 1960s made radical radiotherapy feasible and successful in terms of higher cure rates and longer survival. We are already in a time when a higher number of patients with radiogenic secondary malignancies must be expected.
CASE REPORT
A 12-year-old boy is reported who suffered from an advanced nasopharynx carcinoma and was treated with radical irradiation in 1983. 15 years later he developed a rare microcystic adnexal carcinoma of the auditory canal inside the volume of the target dose. The secondary malignant neoplasm was resected and required another radiation treatment (1 Gy b.i.d.) due to involved margins.
DISCUSSION AND LITERATURE REVIEW
The entity of microcystic carcinoma is discussed with a review of the literature on biology, diagnosis, and treatment.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1007/s00066-005-1323-9
- PMID 15925985
- Persistent URL
- https://sonar.rero.ch/global/documents/114952
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